SCHEMBL6887398

SCHEMBL6887398

CCC(=O)c1cc(CCc2ccc(C(O[SiH](C)C)C(C)(C)C)c(C(O[SiH](C)C)C(C)(C)C)c2)cs1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6889377 0.86 DAO (0.33) DAO
SCHEMBL6888926 0.85
SCHEMBL6886153 0.84 POLB (0.40)
SCHEMBL6890580 0.84
SCHEMBL6883858 0.83 DAO (0.31) DAO
SCHEMBL3279984 0.81 CYP4F2 (0.34)
SCHEMBL6889684 0.80 VDR (0.33)
SCHEMBL6566245 0.80 VDR (0.33)
SCHEMBL6887618 0.79
SCHEMBL5871915 0.75 KDM4E (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706725-B1 BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-03-16 US disclosed