Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13296392 | 0.81 | ALDH1A1 (0.64) | PLK1ALDH1A1TDP1TAS1R3TAS1R1 | |
| SCHEMBL27690322 | 0.81 | SPHK1 (0.59) | PLK1ALDH1A1MAPTKMT2A | |
| SCHEMBL27690344 | 0.81 | SPHK1 (0.59) | PLK1ALDH1A1MAPTKMT2A | |
| SCHEMBL27690329 | 0.81 | SPHK1 (0.59) | PLK1ALDH1A1MAPTKMT2A | |
| SCHEMBL28766283 | 0.81 | SPHK1 (0.59) | PLK1ALDH1A1MAPTKMT2A | |
| SCHEMBL27286194 | 0.81 | SPHK1 (0.59) | PLK1ALDH1A1MAPTKMT2A | |
| SCHEMBL5592702 | 0.80 | HDAC1 (0.51) | ALDH1A1NPC1RAB9ALMNAHPGD | |
| SCHEMBL29033382 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TDP1NPC1RAB9AGAA | |
| SCHEMBL1535943 | 0.79 | PLK1 (0.70) | PLK1ALDH1A1TDP1TAS1R3TAS1R1 | |
| SCHEMBL13479797 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TDP1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780887-B1 | TREATING AND/OR PREVENTING ISCHEMIA, PATHOLOGIES ASSOCIATED WITH ISCHEMIA OR PATHOLOGIES ASSOCIATED WITH MITOCHONDRIAL DEFICIENCIES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-08-24 | — | — | US | disclosed |