Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1974935 | 0.83 | TSHR (0.45) | SELLSELPERN1ALDH1A1TSHR | |
| SCHEMBL18529852 | 0.82 | SELL (0.56) | SELLSELPALDH1A1TSHRKDM4E | |
| SCHEMBL21801190 | 0.82 | ERN1 (0.37) | ERN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30744116 | 0.82 | ERN1 (0.37) | ERN1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1982182 | 0.80 | SELL (0.60) | SELLSELPERN1ALDH1A1TSHR | |
| SCHEMBL30776108 | 0.79 | CYP1A2 (0.41) | ERN1ALDH1A1TSHRRXFP1AKR1C4 | |
| SCHEMBL27659849 | 0.79 | CYP1A2 (0.41) | ERN1ALDH1A1TSHRRXFP1AKR1C4 | |
| SCHEMBL29941520 | 0.78 | SELL (0.64) | SELLSELPALDH1A1TSHRKDM4E | |
| SCHEMBL30084375 | 0.78 | TSHR (0.54) | SELLSELPALDH1A1TSHRKDM4E | |
| SCHEMBL2649879 | 0.78 | SELL (0.64) | SELLSELPALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |