Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.60 |
| ▸ | SELP | P16109 | 1/20 | 0.60 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860525 | 0.84 | SELL (0.79) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL176255 | 0.84 | SELL (0.79) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL6508228 | 0.84 | AKR1C3 (0.47) | SELLSELPERN1AKR1C4AKR1C3 | |
| SCHEMBL78614 | 0.84 | SELL (0.52) | SELLSELPERN1AKR1C4AKR1C3 | |
| SCHEMBL11043522 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL29250135 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL29112577 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL29072927 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL29208048 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 | |
| SCHEMBL29030098 | 0.82 | SELL (0.75) | SELLSELPCYP1A2LDHAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2026-05-28 | — | — | US | disclosed |
| US-20250101011-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2025-03-27 | — | — | US | disclosed |
| EP-4450497-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | Shanghai Yidian Pharmaceutical Technology Development Co., Ltd (CN) | 2024-10-23 | — | — | EP | disclosed |
| CN-118475575-A | Peptidyl nitrile compound and application thereof | 上海壹典医药科技开发有限公司 | 2024-08-09 | — | — | CN | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-104341401-B | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | 北京凯因科技股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-101044403-B | Methods for altering surface characteristics of microspheres | LUMINEX CORP | 2012-10-31 | — | — | CN | disclosed |
| WO-2011075607-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011075607-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | WO | disclosed |
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| CN-101044403-A | Methods for altering surface characteristics of microspheres | LUMINEX CORP (US) | 2007-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101011-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | CTSC, CTSL, CTRL | SELL 1706/4885SELP 705/4885ERN1 1301/4885 |
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, IRF3 | SELL 4179/4885SELP 3614/4885ERN1 75/4885 |
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | JAK1, CTSZ, CTSL | SELL 716/4885SELP 453/4885ERN1 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.