Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 14/20 | 0.64 |
| ▸ | GAA | P10253 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | CYBB | P04839 | 2/20 | 0.64 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.64 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenothiazine SCHEMBL9727549 | 0.94 | NOX1 (0.57) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL28750254 | 0.89 | NOX1 (0.71) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL8158378 | 0.87 | NOX1 (0.68) | NOX1GAAMAPTMEN1KMT2A | |
| Methacrylic Acid SCHEMBL11115741 | 0.85 | NOX1 (0.48) | NOX1GAAMAPTMEN1KMT2A | |
| Thianthrene SCHEMBL8726614 | 0.85 | NOX1 (0.48) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL8158386 | 0.81 | NOX1 (0.65) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL9347283 | 0.80 | NOX1 (0.85) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL27936894 | 0.80 | NOX1 (0.94) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL9483121 | 0.80 | NOX1 (0.63) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL688772 | 0.80 | NOX1 (0.63) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155253-A | Reacting vinyl derivative of first Bronsted acid with labile Bronsted acid in presence of ruthenium catalyst, maintaining concentration below certain level and removing product as formed | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0506070-A2 | Transvinylation process for the preparation of thermally labile vinyl compounds and vinyl compounds prepared from thermally labile acids | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-09-30 | — | — | EP | disclosed |