Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886914 | 0.86 | SLC5A2 (0.38) | GSK3B | |
| SCHEMBL6885088 | 0.85 | GSK3B (0.36) | GSK3BCA1CA2 | |
| SCHEMBL6884989 | 0.85 | GSK3B (0.36) | GSK3BCA1CA2 | |
| SCHEMBL6885551 | 0.85 | GSK3B (0.36) | GSK3BCA1CA2 | |
| SCHEMBL6887384 | 0.85 | GSK3B (0.36) | GSK3BCA1CA2 | |
| SCHEMBL6885777 | 0.84 | NPC1 (0.45) | GSK3BNPC1RAB9A | |
| SCHEMBL6884015 | 0.83 | GSK3B (0.35) | GSK3BCA1CA2 | |
| SCHEMBL6887257 | 0.83 | GSK3B (0.33) | GSK3B | |
| SCHEMBL6887576 | 0.82 | GSK3B (0.34) | GSK3BCA1CA2 | |
| SCHEMBL6882294 | 0.82 | GSK3B (0.34) | GSK3BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |