Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3865516 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNTSHRALDH1A1 | |
| Acetic Acid SCHEMBL28354597 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNTSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL23151913 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL27576509 | 0.92 | ALDH1A1 (0.47) | FFAR3LCKFYNTSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27998238 | 0.92 | — | — | |
| Bicarbonate SCHEMBL28245040 | 0.88 | FFAR3 (0.46) | FFAR3LCKFYNTSHRALDH1A1 | |
| SCHEMBL1190178 | 0.88 | — | — | |
| SCHEMBL30581185 | 0.88 | — | — | |
| SCHEMBL30581182 | 0.88 | — | — | |
| SCHEMBL1332099 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106519308-B | A kind of preparation method of hydroxypropyl methyl cellulose cross linking membrane | 昆明理工大学 | 2019-02-05 | — | — | CN | claimed |
| CN-106519308-A | Preparing method for hydroxypropyl methyl cellulose crosslinked membrane | 昆明理工大学 | 2017-03-22 | — | — | CN | claimed |
| US-6783743-B1 | COMPONENTS AND PRODUCT LOSS ARE SUBSTANTIALLY ELIMINATED BY RECOVERING MATERIALS FROM VARIOUS UNITS OF THE APPARATUS, AND RECYCLING THE MATERIALS BACK TO THE RESPECTIVE UNITS | PURITAN PRODUCTS, INC. | 2004-08-31 | — | — | US | claimed |