⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871026 | 0.73 | HSP90AA1 (0.42) | — | |
| SCHEMBL6007442 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL27462142 | 0.67 | HSP90AA1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28141632 | 0.67 | — | — | |
| SCHEMBL27636940 | 0.67 | — | — | |
| SCHEMBL6767656 | 0.65 | — | — | |
| SCHEMBL9723365 | 0.63 | HSP90AA1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL4760945 | 0.58 | HSP90AA1 (0.47) | — | |
| SCHEMBL1686922 | 0.57 | — | — | |
| SCHEMBL8846350 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502333-A | Organic resin laminate | EXATEC LLC | 2014-01-08 | — | — | CN | disclosed |
| EP-1417207-A2 | PROCESS FOR PREPARING 2-(4-PYRIDYL) AMINO-6-DIALKYLOXYPHENYL-PYRIDO(2,3-D)PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1307451-A2 | PROCESS FOR PREPARING 2-(4-PYRIDYL)AMINO-6-DIALKYLOXYPHENYL-PYRIDO 2,3-D]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY LLC (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1307450-A2 | 2-(4-PYRDYL)AMINO-6-DIALKOXYPHENYL-PYRIDO(2.3-D)PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2003027110-A2 | PROCESS FOR PREPARING 2-(4-PYRIDYL) AMINO-6-DIALKYLOXYPHENYL-PYRIDO [2,3-D]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2002012238-A2 | 2-(4-PYRIDYL)AMINO-6-DIALKOXYPHENYL-PYRIDO[2,3-d]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| WO-2002012237-A2 | PROCESS FOR PREPARING 2-(4-PYRIDYL)AMINO-6-DIALKYLOXYPHENYL-PYRIDO[2,3-D]PYRIMIDIN-7-ONES | WARNER-LAMBERT COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |
| EP-0823908-A1 | PYRIDO 2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034867-A1 | PYRIDO[2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1996-11-07 | — | — | WO | disclosed |