⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320675 | 0.71 | — | — | |
| SCHEMBL437703 | 0.69 | — | — | |
| SCHEMBL6889110 | 0.69 | — | — | |
| SCHEMBL11978709 | 0.65 | — | — | |
| SCHEMBL2238608 | 0.65 | — | — | |
| SCHEMBL6767656 | 0.65 | — | — | |
| SCHEMBL9723365 | 0.63 | HSP90AA1 (0.33) | — | |
| SCHEMBL687678 | 0.62 | — | — | |
| SCHEMBL373166 | 0.60 | HSP90AA1 (0.50) | — | |
| SCHEMBL6007422 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102134242-A | Novel compounds for quickly treating impotence with long-lasting action | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD | 2011-07-27 | — | — | CN | claimed |
| CN-1712403-A | 2-phenyl substituted imidazotriazone compound for treating or preventing from impotence | RADIATION MEDICAL INST MILITAR (CN) | 2005-12-28 | — | — | CN | claimed |
| CN-111423457-A | 1,9 a-dihydropyrido [2,1-c ] [1,4] thiazine compound and preparation method thereof | 深圳职业技术学院 | 2020-07-17 | — | — | CN | disclosed |
| CN-105263472-A | Topical pharmaceutical composition comprising tenofovir and an antibacterial agent and optionally ciclopirox | CIPLA LTD | 2016-01-20 | — | — | CN | disclosed |
| CN-104884063-A | Antiretroviral pharmaceutical compositions | CIPLA LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-102134242-B | Novel compounds for quickly treating impotence with long-lasting action | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-101553483-B | 2-(piperidin-4-yl)-4-phenoxy-or phenylamino-pyrimidine derivatives as non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE | 2013-04-17 | — | — | CN | disclosed |
| CN-101679294-B | Non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE | 2012-08-08 | — | — | CN | disclosed |
| CN-101501002-B | Non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE | 2012-06-27 | — | — | CN | disclosed |
| CN-102134242-A | Novel compounds for quickly treating impotence with long-lasting action | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD | 2011-07-27 | — | — | CN | disclosed |
| CN-101679294-A | Non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE | 2010-03-24 | — | — | CN | disclosed |
| CN-101273020-A | NNRT inhibitors | HOFFMANN LA ROCHE (CH) | 2008-09-24 | — | — | CN | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| CN-1712403-A | 2-phenyl substituted imidazotriazone compound for treating or preventing from impotence | RADIATION MEDICAL INST MILITAR (CN) | 2005-12-28 | — | — | CN | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| CN-1517790-A | Emulsion and material cntaining triazine-thioketone compound for heat development material | ��˹���´﹫˾ | 2004-08-04 | — | — | CN | disclosed |
| CN-1517790-A | Emulsion and material cntaining triazine-thioketone compound for heat development material | ��˹���´﹫˾ | 2004-08-04 | — | — | CN | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |