Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.65 |
| ▸ | ATM | Q13315 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | GAA | P10253 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | GLA | P06280 | 5/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728857 | 0.86 | KDM4E (0.69) | MAPTKDM4EATMHTTRAD52 | |
| SCHEMBL20409289 | 0.83 | KDM4E (0.65) | MAPTKDM4EATMHTTRAD52 | |
| SCHEMBL1146916 | 0.81 | MAPT (1.00) | MAPTKDM4EATMRAD52ALDH1A1 | |
| SCHEMBL69403 | 0.81 | MAPT (0.67) | MAPTKDM4EATMHTTALDH1A1 | |
| SCHEMBL2317692 | 0.81 | MAPT (0.67) | MAPTKDM4EATMRAD52ALDH1A1 | |
| SCHEMBL1821389 | 0.81 | MAPT (0.71) | MAPTKDM4EATMHTTALDH1A1 | |
| SCHEMBL7957662 | 0.81 | MAPT (0.67) | MAPTKDM4EATMHTTRAD52 | |
| SCHEMBL4260350 | 0.81 | MAPT (0.67) | MAPTKDM4EATMHTTRAD52 | |
| SCHEMBL11904084 | 0.81 | MAPT (0.67) | MAPTKDM4EATMHTTRAD52 | |
| SCHEMBL13090974 | 0.79 | KDM4E (0.45) | MAPTKDM4EATMHTTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780828-B2 | Contraceptive compounds and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220388993-A1 | CONTRACEPTIVE COMPOUNDS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-12-08 | — | — | US | disclosed |
| US-9211725-B2 | Inkjet recording method and printed material | FUJIFILM CORPORATION (JP) | 2015-12-15 | — | — | US | disclosed |
| US-9211725-B2 | Inkjet recording method and printed material | FUJIFILM CORPORATION (JP) | 2015-12-15 | — | — | US | disclosed |
| EP-2682272-B1 | INK JET RECORDING METHOD AND PRINTED MATERIAL | FUJIFILM CORP (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8378002-B2 | Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method | FUJIFILM CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8378002-B2 | Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method | FUJIFILM CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8168263-B2 | Photo-curable composition, ink composition, and inkjet recording method using the ink composition | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8168263-B2 | Photo-curable composition, ink composition, and inkjet recording method using the ink composition | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8147921-B2 | Ink set for inkjet recording and inkjet recording method | FUJIFILM CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20080182031-A1 | Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound | FUJIFILM CORPORATION (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1944173-A1 | Ink composition and inkjet recording method using the same | FUJIFILM Corporation (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20070203214-A1 | Synthesis Of Chromanones | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | US | disclosed |
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0905131-B1 | Sulfonamid-substituted chromans, process for their preparation, their use as medicine, and pharmaceutical preparation containing them | AVENTIS PHARMA GMBH (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| US-5955607-A | TREATING CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | HOECHST MARION ROUSSEL DEUTSCHLAND (DE) | 1999-09-21 | — | — | US | disclosed |
| EP-0905131-A1 | Sulfonamid-substituted chromans, process for their preparation, their use as medicine, and pharmaceutical preparation containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |
| EP-0087858-A1 | New chromanone compounds and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780828-B2 | Contraceptive compounds and methods | CYP19A1, GNRHR, NR5A1 | MAPT 4709/4885KDM4E 925/4885ATM 4691/4885 |
| US-20220388993-A1 | CONTRACEPTIVE COMPOUNDS AND METHODS | CYP19A1, GNRHR, NR5A1 | MAPT 4709/4885KDM4E 925/4885ATM 4691/4885 |
| US-20070203214-A1 | Synthesis Of Chromanones | MAP3K6, MAP3K8, MAP3K1 | MAPT 3642/4885KDM4E 1684/4885ATM 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.