Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884243 | 0.82 | AR (0.53) | ARCYP11B2CYP11B1FYNCYP19A1 | |
| SCHEMBL6464131 | 0.74 | AR (0.80) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6464535 | 0.71 | AR (0.67) | ARCYP11B2CYP11B1FYNCYP19A1 | |
| SCHEMBL6464438 | 0.70 | AR (0.73) | ARSLC22A12CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6889336 | 0.70 | AR (0.61) | ARSLC22A12CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6466344 | 0.68 | AR (0.69) | ARCYP11B2CYP11B1XDH | |
| SCHEMBL5251476 | 0.68 | AR (0.60) | ARSLC22A12XDH | |
| SCHEMBL6465272 | 0.66 | AR (1.00) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL4915248 | 0.66 | AR (0.72) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL4921936 | 0.65 | AR (1.00) | ARCYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |