Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464438 | 0.92 | AR (0.73) | ARCYP11B2CYP11B1KDM1ASLC22A12 | |
| SCHEMBL6884237 | 0.80 | AR (0.57) | ARCYP11B2CYP11B1KDM1ACYP19A1 | |
| SCHEMBL6889022 | 0.77 | AR (0.68) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6464131 | 0.76 | AR (0.80) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL15147305 | 0.72 | AR (0.58) | ARCYP11B2CYP11B1 | |
| SCHEMBL6464529 | 0.71 | AR (0.69) | ARCYP11B2CYP11B1KDM1ACYP19A1 | |
| SCHEMBL6889343 | 0.70 | AR (0.60) | ARCYP11B2CYP11B1SLC22A12CYP19A1 | |
| SCHEMBL6466344 | 0.70 | AR (0.69) | ARCYP11B2CYP11B1KDM1A | |
| SCHEMBL6464828 | 0.70 | AR (0.77) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6465272 | 0.68 | AR (1.00) | ARCYP11B2CYP11B1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |