Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889022 | 0.79 | AR (0.68) | ARCYP11B1CYP11B2HSD17B10CYP19A1 | |
| SCHEMBL6466727 | 0.79 | AR (0.60) | ARCYP11B1CYP11B2RIPK3ALDH1A1 | |
| SCHEMBL6468119 | 0.78 | AR (0.49) | ARCYP11B1CYP11B2RIPK3ALDH1A1 | |
| SCHEMBL6464447 | 0.76 | AR (0.53) | ARCYP11B1CYP11B2RIPK3ALDH1A1 | |
| SCHEMBL6468889 | 0.74 | AR (0.86) | ARCYP11B1CYP11B2ALDH1A1KDM4E | |
| SCHEMBL6469486 | 0.74 | AR (0.56) | ARCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6466721 | 0.73 | AR (0.80) | ARCYP11B1CYP11B2RIPK3ALDH1A1 | |
| SCHEMBL6466939 | 0.72 | AR (0.67) | ARMAPTLMNA | |
| SCHEMBL3070156 | 0.72 | SLC2A1 (0.53) | ARCYP11B1CYP11B2RIPK3ALDH1A1 | |
| SCHEMBL6466315 | 0.71 | AR (0.59) | ARCYP11B1CYP11B2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |