Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468889 | 0.88 | AR (0.86) | ARCYP19A1CYP11B2CYP11B1CCNC | |
| SCHEMBL6469486 | 0.84 | AR (0.56) | ARCYP19A1CYP11B2CYP11B1CCNC | |
| SCHEMBL24414502 | 0.84 | AR (0.80) | ARCYP19A1CYP11B2CYP11B1CCNC | |
| SCHEMBL6466939 | 0.82 | AR (0.67) | ARTSHRPTGDR2KLKB1KLK1 | |
| SCHEMBL21996432 | 0.81 | AR (0.76) | ARCYP19A1CYP11B2CYP11B1LOXL2 | |
| SCHEMBL24411064 | 0.81 | AR (0.76) | ARCYP19A1CYP11B2CYP11B1CCNC | |
| SCHEMBL24411088 | 0.81 | AR (0.76) | ARCYP19A1CYP11B2CYP11B1CCNC | |
| SCHEMBL6889627 | 0.81 | AR (0.67) | ARCYP19A1CYP11B2CYP11B1PTGDR2 | |
| SCHEMBL6466315 | 0.81 | AR (0.59) | ARCYP19A1CYP11B2CYP11B1TSHR | |
| SCHEMBL6884237 | 0.81 | AR (0.57) | ARCYP19A1CYP11B2CYP11B1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |