Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170073 | 0.86 | FNTA (0.44) | HTTALDH1A1 | |
| SCHEMBL6884036 | 0.83 | MCL1 (0.46) | XDHSLC22A12MMP12MMP13HTT | |
| SCHEMBL7100618 | 0.73 | POLB (0.44) | HTTADRA1DALDH1A1 | |
| SCHEMBL6163480 | 0.72 | POLB (0.44) | HTTADRA1DALDH1A1 | |
| SCHEMBL7106932 | 0.71 | POLB (0.44) | ALDH1A1 | |
| SCHEMBL7101526 | 0.71 | CYP19A1 (0.43) | XDHSLC22A12HTTBRS3CCR2 | |
| SCHEMBL5085509 | 0.71 | SLC22A12 (0.61) | XDHSLC22A12HTTF11BRS3 | |
| SCHEMBL6165250 | 0.70 | FNTA (0.51) | ALDH1A1 | |
| SCHEMBL15486418 | 0.69 | ELANE (0.48) | XDHCCR2 | |
| SCHEMBL7102321 | 0.69 | POLB (0.43) | BRS3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |