Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.46 |
| ▸ | BAD | Q92934 | 8/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165250 | 0.86 | FNTA (0.51) | MCL1BAD | |
| SCHEMBL6889407 | 0.83 | XDH (0.44) | XDHSLC22A12HTTF11MMP12 | |
| SCHEMBL27531649 | 0.79 | NR4A1 (0.53) | MCL1BADCHRNB2CHRNA4CMA1 | |
| SCHEMBL5085509 | 0.71 | SLC22A12 (0.61) | XDHSLC22A12ADRA2CHTTF11 | |
| SCHEMBL21822526 | 0.70 | CCR9 (0.57) | MCL1HTTCMA1 | |
| SCHEMBL15853175 | 0.69 | ADRA2C (0.54) | MCL1ADRA2CACMSD | |
| SCHEMBL21822506 | 0.68 | CMA1 (0.42) | MCL1BADSLC22A12CMA1F11 | |
| SCHEMBL21822447 | 0.68 | CMA1 (0.42) | SLC22A12HTTCMA1F11 | |
| SCHEMBL31689648 | 0.68 | CMA1 (0.42) | SLC22A12HTTCMA1F11 | |
| SCHEMBL31689693 | 0.68 | CMA1 (0.42) | MCL1BADSLC22A12CMA1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |