Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.62 |
| ▸ | TNF | P01375 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.57 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884837 | 1.00 | ADORA2B (0.62) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6346622 | 0.99 | ADORA2B (0.64) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6346627 | 0.99 | ADORA2B (0.64) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL15790447 | 0.88 | ADORA2B (0.67) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL16120981 | 0.88 | ADORA2B (0.77) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6779520 | 0.88 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6777369 | 0.88 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6778207 | 0.88 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL8686678 | 0.88 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 | |
| SCHEMBL6778919 | 0.88 | ADORA2B (0.66) | ADORA2BTNFUSP2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460074-A1 | Substituted amino alkyl compounds | CELL THERAPEUTICS, INC. (US) | 2004-09-22 | — | — | EP | disclosed |
| US-5889011-A | THERAPY FOR SEPSIS; ORGAN TOXICITY, ALOPECIA, ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES | CELL THERAPEUTICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| US-5817662-A | THERAPY FOR SEPTIC SHOCK, ALOPECIA; INFLAMMATION;AUTOIMMUNE DISEASES | CELL THERAPEUTICS, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0623133-A4 | SUBSTITUTED AMINO ALKYL COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1995-10-11 | — | — | EP | disclosed |
| EP-0623133-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| US-5340813-A | Therapeutical agent can maintain cellular hemeostasis in the face of variety of inflammatory stimuli | CELL THERAPEUTICS, INC. (US) | 1994-08-23 | — | — | US | disclosed |
| WO-1994011370-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |