Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15301825 | 0.94 | POLB (0.62) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15302794 | 0.91 | POLB (0.59) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL17081954 | 0.91 | TDP1 (0.59) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15302403 | 0.91 | POLB (0.67) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL16541364 | 0.90 | TDP1 (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL16921466 | 0.90 | HTT (0.69) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15302790 | 0.88 | POLB (0.63) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL690787 | 0.88 | HTT (0.67) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15303149 | 0.86 | TDP1 (0.56) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL378966 | 0.85 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| EP-2181173-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2181173-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2181173-A1 | LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009030329-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030329-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |