Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689051 | 0.95 | POLB (0.62) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL11229036 | 0.93 | POLB (0.56) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL815993 | 0.92 | POLB (0.65) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL12991026 | 0.90 | POLB (0.59) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL21305315 | 0.89 | HTT (0.62) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL14173280 | 0.89 | HTT (0.68) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14173281 | 0.89 | HTT (0.68) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL11961765 | 0.88 | POLB (0.68) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL688959 | 0.88 | POLB (0.57) | HTTPOLBAPEX1TDP1ELANE | |
| SCHEMBL12242875 | 0.88 | POLB (0.61) | HTTPOLBAPEX1TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710415-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-3710414-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-3642284-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Wacker Chemie AG (DE) | 2020-04-29 | — | — | EP | disclosed |
| WO-2019052660-A1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | WACKER CHEMIE AG (DE) | 2019-03-21 | — | — | WO | disclosed |
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304035-B2 | Liquid crystal display | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| EP-2181173-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2181173-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100309423-A1 | Liquid Crystal Display | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2181173-A1 | LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009030329-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |
| WO-2009030329-A1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-03-12 | — | — | WO | disclosed |