Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 10/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886339 | 0.93 | CHRNA7 (0.39) | CHRNA7AVPR1BCHRNA1CHRNB2CHRNB4 | |
| SCHEMBL6886862 | 0.90 | AVPR1B (0.39) | CHRNA7AVPR1BCHRNA1CHRNB2CHRNB4 | |
| SCHEMBL6887309 | 0.90 | AVPR1B (0.41) | AVPR1BKDM4EAVPR1A | |
| SCHEMBL6886267 | 0.88 | TLR7 (0.37) | CHRNA7AVPR1BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6887249 | 0.87 | CHRNA1 (0.39) | CHRNA7AVPR1BCHRNA1CHRNB2CHRNB4 | |
| SCHEMBL1669105 | 0.84 | TLR7 (0.35) | CHRNA7AVPR1BALDH1A1HSD17B10AVPR1A | |
| SCHEMBL6887594 | 0.84 | CHRNA7 (0.44) | CHRNA7CHRNA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6888036 | 0.84 | CHRNA7 (0.43) | CHRNA7CHRNA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6886312 | 0.84 | HPGD (0.40) | CHRNA7AVPR1BKDM4EALDH1A1HPGD | |
| SCHEMBL6887435 | 0.83 | CHRNA7 (0.43) | CHRNA7CHRNA1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045258-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | N.V. ORGANON (NL) | 2011-04-21 | — | — | WO | disclosed |