SCHEMBL6889850

SCHEMBL6889850

CC/C(=C/C=C/C(O)(CC)CC)c1csc(COc2ccc(C(O)[Si](C)(C)C(C)(C)C)c(C(O)[Si](C)(C)C(C)(C)C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VDR P11473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565004 0.81 VDR (0.44) VDR
SCHEMBL6882675 0.81 VDR (0.40) VDR
SCHEMBL6564516 0.81 VDR (0.40) VDR
SCHEMBL6564519 0.80 VDR (0.46) VDR
SCHEMBL6889853 0.80 VDR (0.46) VDR
SCHEMBL6565009 0.79 VDR (0.62) VDR
SCHEMBL6564994 0.79 VDR (0.62) VDR
SCHEMBL6564999 0.79 VDR (0.62) VDR
SCHEMBL6888558 0.76 VDR (0.41) VDR
SCHEMBL6564525 0.75 VDR (0.41) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6706725-B1 BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-03-16 US disclosed