SCHEMBL688991

SCHEMBL688991

O=C(Oc1cccc(O)c1)c1ccc(C(=O)Oc2cccc(O)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.70
ESR2 Q92731 2/20 0.70
CYP3A4 P08684 1/20 0.63
POLB P06746 1/20 0.51
KMT2A Q03164 6/20 0.51
MEN1 O00255 2/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
NSD2 O96028 1/20 0.50
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
SERPINE1 P05121 1/20 0.47
NR1H4 Q96RI1 1/20 0.46
CLK1 P49759 1/20 0.46
DYRK1A Q13627 1/20 0.46
DYRK1B Q9Y463 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787681 0.96 ESR1 (0.66) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL4640725 0.93 ESR1 (0.62) ESR1ESR2CYP3A4POLBKMT2A
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL78117 0.92 ESR1 (0.71) ESR1ESR2CYP3A4KMT2AMEN1
Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL31650796 0.92 ESR1 (0.71) ESR1ESR2CYP3A4KMT2AMEN1
SCHEMBL4459121 0.91 ESR1 (0.60) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL689959 0.90 ESR1 (0.78) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL10782190 0.90 ESR1 (0.78) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL10784489 0.89 ESR1 (0.66) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL11198376 0.89 ESR1 (0.66) ESR1ESR2CYP3A4POLBKMT2A
SCHEMBL21418171 0.88 ESR1 (0.57) ESR1ESR2CYP3A4POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3628699-B1 COPOLYCARBONATE AND PREPARATION METHOD THEREFOR LG CHEMICAL LTD (KR) 2022-12-28 EP disclosed
CN-110809594-B Copolycarbonates and methods of making the same 株式会社LG化学 2021-12-31 CN disclosed
US-11186682-B2 Copolycarbonate and method for preparing the same LG CHEM, LTD. (KR) 2021-11-30 US disclosed
US-20200148818-A1 COPOLYCARBONATE AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2020-05-14 US disclosed
EP-3628699-A1 COPOLYCARBONATE AND PREPARATION METHOD THEREFOR LG CHEM, LTD. (KR) 2020-04-01 EP disclosed
CN-110809594-A Copolycarbonates and methods of making the same 株式会社LG化学 2020-02-18 CN disclosed
WO-2019156432-A1 COPOLYCARBONATE AND PREPARATION METHOD THEREFOR 주식회사 엘지화학 2019-08-15 WO disclosed
US-9464183-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2016-10-11 US disclosed
US-8222446-B2 Method for producing dihydroxybenzene derivative MITSUI CHEMICALS, INC. (JP) 2012-07-17 US disclosed
EP-1820667-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2012-02-29 EP disclosed
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2011-01-06 US disclosed
EP-2269976-A1 PROCESS FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE Mitsui Chemicals, Inc. (JP) 2011-01-05 EP disclosed
US-7823614-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2010-11-02 US disclosed
US-20090229728-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-09-17 US disclosed
US-20080047650-A1 Rubber Composition And Pneumatic Tire Using The Same BRIDGESTONE CORPORATION (JP) 2008-02-28 US disclosed
CN-101076457-A Pneumatic tire BRIDGESTONE CORP (JP) 2007-11-21 CN disclosed
EP-1820667-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-22 EP disclosed
EP-1724302-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME Bridgestone Corporation (JP) 2006-11-22 EP disclosed
EP-0052927-B1 STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-01-07 EP disclosed
US-3939142-A Phenylazophenyl dyestuff HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE UBE2B, UBE2G2, TUBB2B ESR1 742/4885ESR2 588/4885CYP3A4 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.