TUBB2B

Tubulin beta-2B chain · Q9BVA1 · TUBB2B on Sugi Atlas →

132,530 patent compounds predicted against TUBB2B, 83,760 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Curacin A (SCHEMBL61304)	1.00	20/20
Vintriptol (SCHEMBL93959)	1.00	15/20
Vindesine (SCHEMBL4420)	0.85	13/20
Vindesine (SCHEMBL4421)	0.85	13/20
Vindesine (SCHEMBL4285)	0.85	12/20
SCHEMBL147173	0.50	12/20
SCHEMBL147174	0.50	12/20
Combretastatin (SCHEMBL19955)	1.00	9/20
Combretastatin (SCHEMBL19956)	1.00	9/20
SCHEMBL118593	0.69	9/20
Centaureidin (SCHEMBL9953)	1.00	8/20
Thiocolchicine (SCHEMBL43160)	1.00	8/20
Thiocolchicine (SCHEMBL43161)	1.00	8/20
SCHEMBL68067	0.62	8/20
Fosbretabulin (SCHEMBL66079)	0.61	8/20
Vinorelbine (SCHEMBL4765)	1.00	7/20
Combretastatin A4 (SCHEMBL18945)	1.00	7/20
Combretastatin A4 (SCHEMBL18946)	1.00	7/20
Levofloxacin Anhydrous (SCHEMBL15397)	0.98	7/20
Ofloxacin (SCHEMBL24373)	0.98	7/20

Clinical trials — most relevant to TUBB2B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)	PHASE2/PHASE3	ACTIVE_NOT_RECRUITING
Four Versus Six Cycles of Cyclophosphamide/Doxorubicin or Paclitaxel in Adjuvant Breast Cancer	PHASE3	COMPLETED
First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients	PHASE2	ACTIVE_NOT_RECRUITING
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer	PHASE2	UNKNOWN
A Multicenter Study of NAP (AL-108) in Schizophrenia	PHASE2	COMPLETED
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer	PHASE2	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis	PHASE1/PHASE2	WITHDRAWN
Study of ABT-751 in Patients With Refractory Hematologic Malignancies	PHASE1	COMPLETED
Exploratory Evaluation of [11C]MPC6827	EARLY_PHASE1	COMPLETED
Diagnostic of Chemotherapy Induced Neuropathy in Children	nan	COMPLETED
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
Effect of Low Dose of Colchicine on Platelet Reactivity	nan	COMPLETED
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
The Relation of Microtubule-Associated Protein 2 and Cell Migration	nan	UNKNOWN
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting	nan	UNKNOWN
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method)	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Association Between Luminal Bile Salt Content and Duodenal Mucosal Integrity in Functional Dyspepsia	nan	COMPLETED
Myotubular Myopathy Genetic Testing Study	nan	COMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS	nan	RECRUITING
WGS of Korean Idiopathic Bronchiectasis	nan	UNKNOWN
Newborn Screening for Spinal Muscular Atrophy	nan	COMPLETED
Differential Study of Muscle Transcriptome	nan	COMPLETED
Identification of Viable Human Embryos Using Three Different Methods	nan	COMPLETED
Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TUBB2B binder may also engage these)

Protein	Name	Similarity
Q6B856	—	1.000	Q6B856 →
TUBB2A	Tubulin beta-2A chain	1.000	landscape →
P85108	—	1.000	P85108 →
P69893	—	1.000	P69893 →
P11833	—	1.000	P11833 →
Q27U48	—	1.000	Q27U48 →
Q6GLE7	—	1.000	Q6GLE7 →
O44388	—	1.000	O44388 →
Q3MHM5	—	1.000	Q3MHM5 →
P68372	—	1.000	P68372 →
P46265	—	1.000	P46265 →
P32882	—	1.000	P32882 →
Q2HJ81	—	1.000	Q2HJ81 →
P12456	—	1.000	P12456 →
P09203	—	1.000	P09203 →
Q4R4X8	—	1.000	Q4R4X8 →
O59837	—	1.000	O59837 →
P02554	—	1.000	P02554 →
P30883	—	1.000	P30883 →
P61858	—	1.000	P61858 →
Q9NFZ7	—	1.000	Q9NFZ7 →
P41937	—	1.000	P41937 →
Q24560	—	1.000	Q24560 →
P33127	—	1.000	P33127 →
Q4R5B3	—	1.000	Q4R5B3 →
P14140	—	1.000	P14140 →
Q767L7	—	1.000	Q767L7 →
Q2KJD0	—	1.000	Q2KJD0 →
P09244	—	1.000	P09244 →
P69895	—	1.000	P69895 →