Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 8/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494363 | 0.78 | KDM4E (0.56) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL6886449 | 0.77 | IMPDH2 (0.56) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL6493179 | 0.77 | IMPDH2 (0.56) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL16388851 | 0.72 | IMPDH2 (0.58) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL8551555 | 0.72 | CYP1A2 (0.47) | — | |
| SCHEMBL16370951 | 0.70 | IMPDH2 (0.66) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL20877678 | 0.69 | IMPDH2 (0.52) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL1473513 | 0.69 | IMPDH2 (0.74) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL6482542 | 0.68 | IMPDH2 (0.45) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL12021891 | 0.68 | CFTR (0.44) | AAK1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018462-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |