Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890040 | 1.00 | ALOX5AP (0.33) | ALOX5APMEN1NPC1MAPTRAB9A | |
| SCHEMBL6887145 | 0.92 | ALOX5AP (0.33) | ALOX5APMAOBMAOAARCYP3A4 | |
| SCHEMBL6887141 | 0.92 | ALOX5AP (0.33) | ALOX5APMAOBMAOAARCYP3A4 | |
| SCHEMBL6564880 | 0.90 | MAOB (0.32) | MAPTMAOBMAOA | |
| SCHEMBL6564886 | 0.90 | MAOB (0.32) | MAPTMAOBMAOA | |
| SCHEMBL6888103 | 0.87 | ALOX5AP (0.35) | ALOX5APMEN1NPC1MAPTRAB9A | |
| SCHEMBL6888099 | 0.87 | ALOX5AP (0.35) | ALOX5APMEN1NPC1MAPTRAB9A | |
| SCHEMBL6886887 | 0.84 | MRGPRX4 (0.32) | ALOX5APMEN1NPC1MAPTRAB9A | |
| SCHEMBL6886891 | 0.84 | MRGPRX4 (0.32) | ALOX5APMEN1NPC1MAPTRAB9A | |
| SCHEMBL6565100 | 0.81 | MAOB (0.32) | MAPTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |