Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886891 | 1.00 | MRGPRX4 (0.32) | MRGPRX4MEN1NPC1MAPTRAB9A | |
| SCHEMBL6564879 | 0.90 | MRGPRX4 (0.34) | MRGPRX4MAPTSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL6564885 | 0.90 | MRGPRX4 (0.34) | MRGPRX4MAPTSMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL6886943 | 0.87 | NPC1 (0.35) | MRGPRX4MEN1NPC1MAPTRAB9A | |
| SCHEMBL6886939 | 0.87 | NPC1 (0.35) | MRGPRX4MEN1NPC1MAPTRAB9A | |
| SCHEMBL6890040 | 0.84 | ALOX5AP (0.33) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL6890035 | 0.84 | ALOX5AP (0.33) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL6886767 | 0.80 | ALOX5AP (0.40) | MRGPRX4ALOX5AP | |
| SCHEMBL6886768 | 0.80 | ALOX5AP (0.40) | MRGPRX4ALOX5AP | |
| SCHEMBL6887141 | 0.78 | ALOX5AP (0.33) | ALOX5APMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |