Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048860 | 0.67 | — | — | |
| SCHEMBL497572 | 0.66 | LIPA (0.40) | ALDH1A1GAA | |
| SCHEMBL2568051 | 0.66 | LIPA (0.40) | ALDH1A1GAA | |
| SCHEMBL7132308 | 0.66 | LIPA (0.40) | ALDH1A1GAA | |
| SCHEMBL15261953 | 0.66 | LIPA (0.40) | ALDH1A1GAA | |
| SCHEMBL6723241 | 0.65 | LIPA (0.40) | GAA | |
| SCHEMBL3000581 | 0.64 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL23885014 | 0.64 | LIPA (0.39) | GAA | |
| SCHEMBL18297885 | 0.64 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL6814313 | 0.64 | LIPA (0.39) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235023-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | JACOBSEN ERIC N (US) | 2004-11-25 | — | — | US | disclosed |
| US-6709824-B2 | SCREENING SAMPLE FOR CATALYST; GENERATE LIBRARY OF CATALYST, SCREEN LIBRARY, RECOVER CATALYST | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-03-23 | — | — | US | disclosed |
| US-6489093-B1 | THE PRESENT INVENTION PROVIDES METHODS AND COMPOSITIONS, I.E. SYNTHETIC LIBRARIES OF BINDING MOITIES, FOR METAL ATOM OR TO NON-METAL IONS, E.G., CATIONIC OR ANIONIC MOLECULES. | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-12-03 | — | — | US | disclosed |
| US-20020102612-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | JACOBSEN ERIC N (US) | 2002-08-01 | — | — | US | disclosed |
| US-6316616-B1 | USED AS CATALYST TO CATALYZE A CHEMOSELECTIVE, REGIOSELECTIVE, STEREOSELECTIVE OR ENANTIOSELECTIVE TRANSFORMATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-11-13 | — | — | US | disclosed |
| EP-1066228-A1 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051546-A9 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | HARVARD COLLEGE (US) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999051546-A1 | PARALLEL COMBINATORIAL APPROACH TO THE DISCOVERY AND OPTIMIZATION OF CATALYSTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102612-A1 | Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof | COASY, DCXR, LSS | ALDH1A1 741/4885GAA 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.