Methacrylic Acid

Methacrylic Acid

SCHEMBL689063

C=C(C)C(=O)O.C=C(OC(=C)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL160133 0.82 THRB (0.31) THRB
Perflubutane SCHEMBL5248074 0.80 THRB (0.46) THRBTDP1
Perflutren SCHEMBL29016436 0.80 THRB (0.40) THRBTDP1
Methacrylic Acid SCHEMBL689064 0.79 THRB (0.32) THRB
Methacrylic Acid SCHEMBL31316646 0.78 THRB (0.50) THRBTDP1LMNA
SCHEMBL3440820 0.75 THRB (0.40) THRB
SCHEMBL1176844 0.73 THRB (0.44) THRBLMNA
SCHEMBL7184930 0.73 THRB (0.44) THRBLMNA
SCHEMBL21643620 0.73 THRB (0.44) THRBLMNA
SCHEMBL10904474 0.73 THRB (0.44) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507601-B2 Method using fluoropolymer emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-08-13 US disclosed
EP-2499198-B1 FLUOROPOLYMER EMULSIONS DU PONT (US) 2013-07-17 EP disclosed
US-8329822-B2 Fluoropolymer emulsions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
US-8314037-B2 Fluoropolymer emulsions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-20 US disclosed
EP-2499198-A1 FLUOROPOLYMER EMULSIONS E. I. du Pont de Nemours and Company (US) 2012-09-19 EP disclosed
EP-2217630-B1 FLUOROPOLYMER EMULSIONS DU PONT (US) 2012-02-29 EP disclosed
US-20110111659-A1 METHOD USING FLUOROPOLYMER EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-12 US disclosed
US-20110112233-A1 FLUOROPOLYMER EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-12 US disclosed
WO-2011056525-A1 FLUOROPOLYMER EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-12 WO disclosed
EP-2217630-A1 FLUOROPOLYMER EMULSIONS E. I. du Pont de Nemours and Company (US) 2010-08-18 EP disclosed
WO-2009076109-A1 FLUOROPOLYMER EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-18 WO disclosed
US-20090149096-A1 FLUOROPOLYMER EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 US disclosed
US-20090148653-A1 FLUOROPOLYMER EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 US disclosed