Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.67 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890723 | 1.00 | LMNA (1.00) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL16765969 | 0.98 | LMNA (0.97) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL902324 | 0.84 | LMNA (1.00) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL372572 | 0.84 | LMNA (1.00) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL5717630 | 0.83 | LMNA (0.73) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL30209642 | 0.83 | LMNA (0.73) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL5717629 | 0.83 | LMNA (0.73) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL5093226 | 0.82 | KDM4E (0.69) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL5093238 | 0.82 | KDM4E (0.69) | LMNAKDM4EMAPTSMN1; SMN2HTT | |
| SCHEMBL3532094 | 0.80 | HDAC6 (1.00) | LMNAKDM4EMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018462-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |
| US-3989708-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |