Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 14/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802602 | 0.91 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL6891135 | 0.85 | CHRM1 (0.57) | CHRM1ADAM17 | |
| SCHEMBL12803410 | 0.80 | CHRM1 (0.56) | CHRM1 | |
| SCHEMBL12803343 | 0.80 | CHRM1 (0.58) | CHRM1ADAM17 | |
| SCHEMBL2363327 | 0.80 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL12803798 | 0.80 | CHRM1 (0.54) | CHRM1 | |
| SCHEMBL6890091 | 0.79 | ADAM17 (0.41) | CHRM1ADAM17 | |
| SCHEMBL12803113 | 0.79 | CHRM1 (0.58) | CHRM1 | |
| SCHEMBL12803223 | 0.79 | CHRM1 (0.63) | CHRM1ADAM17 | |
| SCHEMBL12958957 | 0.78 | CHRM1 (0.58) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084368-A1 | QUINOLINE AMIDE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |