SCHEMBL6890746

SCHEMBL6890746

O=C(O)CCCCCN(C(=O)CI)N1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
PTGS1 P23219 4/20 0.34
PTGS2 P35354 4/20 0.34
KDM4C Q9H3R0 8/20 0.33
KDM5A P29375 3/20 0.33
PHF8 Q9UPP1 3/20 0.33
KDM4A O75164 7/20 0.33
F13A1 P00488 3/20 0.33
KDM7A Q6ZMT4 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1742918 0.74
SCHEMBL2172604 0.72 KDM4E (0.33) GAAKDM5A
Octanedioate SCHEMBL7080168 0.69 TSHR (0.55) LMNATSHRNFKB1PMP22MEN1
SCHEMBL31419341 0.69 BLM (0.33) PMP22
Azelaic Acid SCHEMBL28918234 0.68 TSHR (0.52) LMNATSHRNFKB1PMP22MEN1
Octanedioate SCHEMBL6037661 0.68 TSHR (0.52) LMNATSHRNFKB1PMP22MEN1
Sebacic Acid SCHEMBL28228671 0.68 TSHR (0.52) LMNATSHRNFKB1PMP22MEN1
Octanedioate SCHEMBL1394807 0.68 TSHR (0.52) LMNATSHRNFKB1PMP22MEN1
SCHEMBL16500059 0.68 PTGS1 (0.47) TSHRMEN1KMT2APTGS1PTGS2
Adipic Acid SCHEMBL906129 0.66 LMNA (0.50) LMNATSHRNFKB1PMP22MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1409728-A2 NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2004-04-21 EP disclosed
WO-2002081739-A2 NON-ENZYMATIC LIPOSOME-LINKED CLOSELY SPACED ARRAY ELECTRODES ASSAY (NEL-ELA) FOR DETECTING AND QUANTIFYING NUCLEIC ACIDS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2002-10-17 WO disclosed