Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511577 | 0.92 | PTGS2 (0.58) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6513503 | 0.87 | PTGS2 (0.68) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6516374 | 0.86 | PTGS2 (0.56) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6511302 | 0.85 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL6516286 | 0.85 | PTGS2 (0.61) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6516195 | 0.85 | PTGS2 (0.68) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6889301 | 0.85 | PTGS2 (0.48) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6512823 | 0.84 | PTGS2 (0.51) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6517851 | 0.84 | PTGS2 (0.60) | PTGS2PDPK1PTGS1 | |
| SCHEMBL6513176 | 0.83 | PTGS2 (0.61) | PTGS2PDPK1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER INC. | 2004-08-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGS1, PTGER1 | PTGS2 29/4885PDPK1 3634/4885PTGS1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.