SCHEMBL6891178

SCHEMBL6891178

C1=C(C(c2ccccc2)(c2ccccc2)C2c3ccccc3-c3ccccc32)CCC1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12815225 0.77 GPR3 (0.38) TSHR
Hydrochloric Acid SCHEMBL7195300 0.70 MAPT (0.31)
SCHEMBL38651730 0.68
SCHEMBL1539669 0.66 GPR3 (0.38) TSHR
SCHEMBL38651497 0.65
SCHEMBL38651648 0.64
SCHEMBL38651499 0.64
SCHEMBL18261170 0.63 MEN1 (0.41)
SCHEMBL8970933 0.63 TSHR (0.42) TSHR
SCHEMBL12815279 0.63 GPR3 (0.40) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6713426-B1 METHYL(PHENYL)METHYLENE)(9-FLUORENYL)(CYCLOPENTADIENYL) ZIRCONIUM DICHLORIDE OR THE (DIPHENYLMETHYLENE) COMPLEX; VERY HIGH MOLECULAR WEIGHT, NARROW MOLECULAR WEIGHT DISTRIBUTION; MOLDINGS ARE TRANSPARENT, FLEXIBLE, TEAR RESISTANT, AND GLOSSY BASELL POLYOLEFINE GMBH (DE) 2004-03-30 US disclosed
EP-0791611-B1 Process for the preparation of cycloolefin polymers TICONA GMBH (DE) 2003-02-12 EP disclosed
EP-0690078-B1 Cycloolefin polymers TICONA GMBH (DE) 2001-03-21 EP disclosed
EP-0700937-B1 Process for preparing ethylene polymers TARGOR GMBH (DE) 2000-02-16 EP disclosed
EP-0399348-B1 Process for preparing ethylenpolymers TARGOR GMBH (DE) 1998-05-20 EP disclosed
US-5731254-A CATALYST HOECHST (DE) 1998-03-24 US disclosed
EP-0407870-B1 Process for preparing cycloolefin polymers HOECHST AG (DE) 1997-12-10 EP disclosed
US-5663268-A Syndiotactic propylene copolymers HOECHST (DE) 1997-09-02 US disclosed
EP-0791611-A2 Process for the preparation of cycloolefin polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-27 EP disclosed
EP-0773242-A2 Process for preparing cycloolefin polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-14 EP disclosed
EP-0516019-A2 Process for preparing syndiotactic polyolefins with large molecular weight distribution HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-02 EP disclosed
WO-1992017544-A1 ALLOYS OF CYCLOOLEFIN POLYMERS AND POLYARYLETHER KETONES HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-15 WO disclosed
WO-1992016585-A1 ALLOYS OF CYCLOOLEFIN POLYMERS AND LIQUID-CRYSTAL POLYESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-01 WO disclosed
US-5087677-A Catalyst of a metallocene and an aluminoxane HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-11 US disclosed
EP-0433987-A2 Process for preparing a syndiotactic propylene copolymer HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-26 EP disclosed
EP-0433986-A2 Process for preparing a polypropylene molding composition HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-26 EP disclosed
EP-0407870-A2 Process for preparing cycloolefin polymers HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-16 EP disclosed
EP-0399348-A2 Process for preparing ethylenpolymers HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-28 EP disclosed
EP-0387691-A1 Process for preparing a syndiotactic polyolefin HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP disclosed
EP-0387690-A1 Process for preparing a syndiotactic polyolefin HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP disclosed