Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089880 | 0.70 | GAA (0.37) | MAPT | |
| SCHEMBL332450 | 0.68 | MEN1 (0.36) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL11172334 | 0.66 | — | — | |
| SCHEMBL6891183 | 0.63 | KDM4E (0.37) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL19471848 | 0.63 | GSK3B (0.46) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL131636 | 0.61 | GSK3B (0.50) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL20504712 | 0.61 | GSK3B (0.44) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL334824 | 0.61 | GSK3B (0.44) | KDM4ELMNATDP1GSK3BCASP3 | |
| Phthalimide SCHEMBL7521038 | 0.60 | GSK3B (0.94) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL331978 | 0.60 | GSK3B (0.42) | KDM4ELMNATDP1GSK3BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |