Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FER | P16591 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036467 | 0.64 | MEN1 (0.38) | KDM4ELMNATDP1GSK3BCASP7 | |
| SCHEMBL28660 | 0.64 | GSK3B (0.44) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL6891180 | 0.63 | KDM4E (0.42) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL1551145 | 0.61 | GSK3B (0.41) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL1450780 | 0.60 | CA12 (0.45) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL334824 | 0.60 | GSK3B (0.44) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL131636 | 0.60 | GSK3B (0.50) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL20504712 | 0.60 | GSK3B (0.44) | KDM4ELMNATDP1GSK3BCASP3 | |
| SCHEMBL8123268 | 0.59 | LRRK2 (0.55) | KDM4ELMNAGSK3BCASP3CASP2 | |
| Phthalimide SCHEMBL932346 | 0.59 | GSK3B (0.94) | KDM4ELMNATDP1GSK3BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |