⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetylene SCHEMBL619305 | 0.77 | APP (0.60) | — | |
| Diphenylacetylene SCHEMBL339222 | 0.77 | APP (0.60) | — | |
| Phenylacetylene SCHEMBL4884 | 0.65 | — | — | |
| Phenylacetylene SCHEMBL1331558 | 0.65 | — | — | |
| Phenylacetylene SCHEMBL4297769 | 0.65 | — | — | |
| Phenylacetylene SCHEMBL1331398 | 0.65 | — | — | |
| Phenylacetylene SCHEMBL1331408 | 0.65 | — | — | |
| Phenylacetylene SCHEMBL6891916 | 0.65 | APP (0.53) | — | |
| Diphenylacetylene SCHEMBL29188592 | 0.63 | APP (1.00) | — | |
| Diphenylacetylene SCHEMBL960609 | 0.63 | APP (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107233925-B | Preparation method of ruthenium carbene catalyst | 中国石油化工股份有限公司 | 2020-04-07 | — | — | CN | claimed |
| EP-0428188-A2 | Novel immunoconjugates and methods for their use in tumor therapy | ONCOGEN (US) | 1991-05-22 | — | — | EP | claimed |
| EP-0253202-A2 | Novel immunoconjugates and methods for their use in tumor therapy | ONCOGEN (US) | 1988-01-20 | — | — | EP | claimed |
| CN-107233925-B | Preparation method of ruthenium carbene catalyst | 中国石油化工股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-107233925-B | Preparation method of ruthenium carbene catalyst | 中国石油化工股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| US-20040151627-A1 | Methods for covalently attaching nucleic acids to substrates | SCIENCE & TECHNOLOGY CORPORATION @ UNM | 2004-08-05 | — | — | US | disclosed |
| WO-2004050830-A2 | METHODS FOR COVALENTLY ATTACHING PROTEINS TO SUBSTRATES | SCIENCE AND TECHNOLOGY CORPORATION @ UNIVERSITY OF NEW MEXICO (US) | 2004-06-17 | — | — | WO | disclosed |
| WO-1993000109-A1 | METHOD OF STIMULATING IMMUNE RESPONSE USING GROWTH HORMONE | GENENTECH, INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| EP-0278501-A2 | Nucleotide analogs, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4007089-A | Method for binding biologically active compounds | NELSON RESEARCH & DEVELOPMENT COMPANY (US) | 1977-02-08 | — | — | US | disclosed |