⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456363 | 0.80 | TSHR (0.42) | — | |
| SCHEMBL9500691 | 0.67 | — | — | |
| SCHEMBL4787202 | 0.65 | THRB (0.37) | — | |
| SCHEMBL8365338 | 0.63 | — | — | |
| SCHEMBL4441116 | 0.63 | — | — | |
| SCHEMBL7050994 | 0.63 | — | — | |
| SCHEMBL3071574 | 0.60 | TSHR (0.42) | — | |
| SCHEMBL4141535 | 0.58 | TSHR (0.39) | — | |
| SCHEMBL5944923 | 0.41 | TSHR (1.00) | — | |
| SCHEMBL8994190 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171368-B | The method of immobilized nucleic acids on carrier | 皇家飞利浦电子股份有限公司 | 2017-06-20 | — | — | CN | disclosed |
| JP-3588115-B2 | — | — | 2004-11-10 | — | — | JP | disclosed |
| US-5652345-A | THERMALLY STABLE DIOXETANE TRIGGERED BY GALACTOSIDASE TO GENERATE CHEMILUMINESCENCE IN AQUEOUS SOLUTION | TROPIX, INC. (US) | 1997-07-29 | — | — | US | disclosed |
| US-5616729-A | FLUORESCENCE | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5438146-A | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1995-08-01 | — | — | US | disclosed |