SCHEMBL6891584

SCHEMBL6891584

O=C(O)c1ccc(Oc2ccccc2Oc2ccccc2)cc1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.66
PYGL P06737 8/20 0.57
HPSE Q9Y251 1/20 0.56
PYGM P11217 9/20 0.56
KDM4E B2RXH2 1/20 0.55
TDP1 Q9NUW8 2/20 0.53
GALK1 P51570 1/20 0.53
CASP6 P55212 1/20 0.53
MCL1 Q07820 1/20 0.53
PLEC Q15149 1/20 0.53
ALDH1A1 P00352 1/20 0.51
CTNNB1 P35222 1/20 0.51
TTR P02766 1/20 0.49
AKR1C3 P42330 1/20 0.49
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969637 0.96 POLB (0.65) POLBPYGLHPSEPYGMKDM4E
SCHEMBL29664286 0.96 POLB (0.65) POLBPYGLHPSEPYGMKDM4E
SCHEMBL28650646 0.95 POLB (0.63) POLBPYGLHPSEPYGMKDM4E
SCHEMBL522949 0.91 POLB (0.77) POLBPYGLHPSEPYGMKDM4E
SCHEMBL30287662 0.91 POLB (0.77) POLBPYGLHPSEPYGMKDM4E
SCHEMBL11059819 0.90 POLB (0.59) POLBPYGLHPSEPYGMKDM4E
SCHEMBL28634306 0.89 POLB (0.61) POLBPYGLHPSEPYGMKDM4E
SCHEMBL28576596 0.89 POLB (0.75) POLBPYGLHPSEPYGMKDM4E
SCHEMBL7258190 0.88 POLB (0.65) POLBPYGLHPSEPYGMKDM4E
SCHEMBL7257602 0.88 POLB (0.59) POLBPYGLHPSEPYGMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
EP-1487900-A1 PREPARATION OF POLYIMIDE POLYMERS GENERAL ELECTRIC COMPANY (US) 2004-12-22 EP disclosed
WO-2003080709-A1 PREPARATION OF POLYIMIDE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-10-02 WO disclosed
EP-0618945-A1 FIRE RETARDING THERMOFORMABLE BLENDS OF COPOLYMER RESINS. GEN ELECTRIC (US) 1994-10-12 EP disclosed
WO-1984003899-A1 BLENDS OF POLYETHERIMIDES AND RUBBER MODIFIED VINYL AROMATIC POLYMERS GEN ELECTRIC (US) 1984-10-11 WO disclosed
US-4382126-A Preparation of aqueous coating composition comprising polyimide-forming reactants GENERAL ELECTRIC COMPANY (US) 1983-05-03 US disclosed
US-4332708-A FLEXIBLE POLYIMIDE COATING FOR WIRES GENERAL ELECTRIC COMPANY (US) 1982-06-01 US disclosed
US-3998840-A MELT POLYMERIZATION OF AN AROMATIC BIS(ETHER-ANHYDRIDE) AND AN ORGANIC DIAMINE GENERAL ELECTRIC COMPANY (US) 1976-12-21 US disclosed