Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | PYGL | P06737 | 8/20 | 0.53 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 9/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GALK1 | P51570 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257602 | 0.97 | POLB (0.59) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL7785071 | 0.92 | POLB (0.60) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL3919045 | 0.89 | POLB (0.55) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL6891584 | 0.88 | POLB (0.66) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL7969637 | 0.88 | POLB (0.65) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL29664286 | 0.88 | POLB (0.65) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL28650646 | 0.86 | POLB (0.63) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL28480681 | 0.86 | GALK1 (0.53) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL30287662 | 0.86 | POLB (0.77) | POLBPYGLHPSEPYGMTDP1 | |
| SCHEMBL522949 | 0.86 | POLB (0.77) | POLBPYGLHPSEPYGMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031853-A1 | Melt processable PMR-type polyimides | UNIVERSITY OF AKRON, THE | 2001-10-18 | — | — | US | claimed |
| US-6642348-B2 | Low melt viscosity, for high performance polymer matrix composites | THE UNIVERSITY OF AKRON | 2003-11-04 | — | — | US | disclosed |
| US-20010031853-A1 | Melt processable PMR-type polyimides | UNIVERSITY OF AKRON, THE | 2001-10-18 | — | — | US | disclosed |