SCHEMBL6891689

SCHEMBL6891689

C#Cc1cc(C#C)c(C#C)c(C#C)c1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL938260 0.75 PTPN1 (0.30)
SCHEMBL2806688 0.74 PTPN1 (0.35) CYP1A1CYP1B1HDAC8
SCHEMBL2810137 0.74 CYP1A1 (0.34) CYP1A1CYP1B1HDAC8
SCHEMBL2806548 0.74 CYP1A1 (0.34) CYP1A1CYP1B1HDAC8
SCHEMBL16566706 0.74 CYP1A1 (0.34) CYP1A1CYP1B1HDAC8
SCHEMBL211753 0.73 CYP1A1 (0.46) CYP1A1CYP1B1HDAC8
SCHEMBL9128254 0.70 VCAM1 (0.37)
SCHEMBL2888713 0.69 CYP1A1 (0.31) CYP1A1CYP1B1HDAC8
SCHEMBL29029260 0.69 CYP1A1 (0.31) CYP1A1CYP1B1
SCHEMBL28522318 0.69 PDE2A (0.31) CYP1A1CYP1B1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762085-A A kind of poly- aryne nanometer sheet of Novel compressive and preparation method thereof 中国科学院合肥物质科学研究院 2019-05-17 CN claimed
CN-109762085-A A kind of poly- aryne nanometer sheet of Novel compressive and preparation method thereof 中国科学院合肥物质科学研究院 2019-05-17 CN disclosed
US-6795230-B1 Self-assembled molecular color switch HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-09-21 US disclosed