SCHEMBL689178

SCHEMBL689178

O=C(Br)c1cccc(C(=O)Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PARP1 P09874 2/20 0.44
TP53 P04637 1/20 0.43
KCNK3 O14649 1/20 0.43
KCNK9 Q9NPC2 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA9 Q16790 2/20 0.42
CA2 P00918 1/20 0.42
CA6 P23280 1/20 0.42
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
FOLH1 Q04609 1/20 0.41
DAO P14920 1/20 0.41
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22832308 0.92 ATM (0.65) ATMTDP1L3MBTL1ALDH1A1HSD17B10
SCHEMBL392310 0.90 CA12 (0.58) ATMTDP1L3MBTL1TP53CA12
SCHEMBL22832286 0.87 KMO (0.56) HDAC8
SCHEMBL14862050 0.86 ATM (0.78) ATMTDP1L3MBTL1ALDH1A1MEN1
SCHEMBL8681033 0.85 PARP1 (0.65) L3MBTL1PARP1TP53TSHRALDH1A1
SCHEMBL28151822 0.85 CA12 (0.64) PARP1TP53CA12CA1CA9
SCHEMBL16787644 0.84 GSK3B (0.59) ATMTDP1L3MBTL1
SCHEMBL2179300 0.83 PARP1 (0.63) L3MBTL1PARP1KCNK3KCNK9ALDH1A1
SCHEMBL6113520 0.83 PARP1 (0.63) TDP1PARP1TP53KCNK3KCNK9
SCHEMBL4951090 0.83 PRSS1 (0.50) CA1CA9CA2HDAC6FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
US-20230265585-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF AQUAPORIN A/S (DK) 2023-08-24 US claimed
EP-4171787-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF Aquaporin A/S (DK) 2023-05-03 EP claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN claimed
CN-115867374-A Hollow fiber and method for producing same 水通道蛋白有限公司 2023-03-28 CN claimed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN claimed
WO-2022002788-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF AQUAPORIN A/S (DK) 2022-01-06 WO claimed
EP-3762447-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2021-01-13 EP claimed
US-20200407508-A1 METHOD FOR PRODUCING FIBERS, FILMS AND MOLDINGS OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2020-12-31 US claimed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN claimed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO claimed
US-9974992-B2 Fire extinguishing composition comprising carboxylic acid derivative XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-05-22 US claimed
EP-3095488-A1 FIRE EXTINGUISHING COMPOSITION COMPRISING CARBOXYLIC ACID DERIVATIVE Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) 2016-11-23 EP claimed
US-20160332015-A1 Fire Extinguishing Composition Comprising Carboxylic Acid Derivative NANO FIRE, LLC 2016-11-17 US claimed
US-9346023-B2 Flux enhancing agent for improving composite polyamide reverse osmosis membrane performance GENERAL ELECTRIC COMPANY (US) 2016-05-24 US claimed
EP-2888030-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE!OSMOSIS MEMBRANE PERFORMANCE General Electric Company (US) 2015-07-01 EP claimed
WO-2014031271-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE|OSMOSIS MEMBRANE PERFORMANCE GENERAL ELECTRIC COMPANY (US) 2014-02-27 WO claimed
US-20140054228-A1 Novel Flux Enhancing Agent for Improving Composite Polyamide Reverse Osmosis Membrane Performance GENERAL ELECTRIC COMPANY (US) 2014-02-27 US claimed
US-4123420-A Aromatic copolyester composition containing phosphorus compounds UNITIKA LTD. (JP) 1978-10-31 US claimed