SCHEMBL6891978

SCHEMBL6891978

Cc1cn([C@H]2C[C@H](O)[C@@H](COC(=O)OCC(C)c3ccccc3[N+](=O)[O-])O2)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
BCHE P06276 1/20 0.47
TYMS P04818 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2521252 1.00 POLB (0.47) POLBBCHETYMS
SCHEMBL13666501 1.00 POLB (0.47) POLBBCHETYMS
SCHEMBL7269281 0.92 POLB (0.47) POLBBCHETYMS
SCHEMBL6891120 0.92 POLB (0.47) POLBBCHETYMS
SCHEMBL7645970 0.92 POLB (0.47) POLBBCHE
SCHEMBL8722091 0.92 POLB (0.47) POLBBCHE
SCHEMBL7647601 0.91 POLB (0.46) POLBBCHETYMS
SCHEMBL8719340 0.91 POLB (0.46) POLBBCHETYMS
SCHEMBL7643615 0.91 RNASE1 (0.51)
SCHEMBL6830921 0.90 TYMS (0.49) POLBBCHETYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1159064-B1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2004-04-28 EP disclosed
US-6552182-B2 Gel or viscous liquid of polymer compounds and water, water/ alcohol mixtures and polar aprotic solvents is coated on the nucleoside and irradiated NIGU CHEMIE GMBH (DE) 2003-04-22 US disclosed
US-20020053508-A1 Method for photolytically deprotecting immobilized nucleoside derivatives, especially in the production of DNA chips NIGU CHEMIE GMBH 2002-05-09 US disclosed
EP-0797580-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 2002-04-10 EP disclosed
US-5763599-A FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP Pfleiderer, Wolfgang (DE) 1998-06-09 US disclosed