SCHEMBL6892151

SCHEMBL6892151

Nc1ccccc1-c1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.58
▸ STAT1 P42224 1/20 0.58
▸ NPC1 O15118 4/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ GAA P10253 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ GLA P06280 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ DCUN1D1 Q96GG9 1/20 0.33
▸ TOP1 P11387 1/20 0.32
▸ IDO1 P14902 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011854 0.97 STAT3 (0.60) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL7257242 0.91 STAT3 (0.72) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL7261943 0.85 STAT3 (0.48) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL29154454 0.85 STAT3 (0.63) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL21645270 0.85 NPC1 (0.43) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL7257951 0.84 STAT3 (0.56) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL6034345 0.84 STAT3 (0.47) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL7257311 0.84 STAT3 (0.56) STAT3STAT1NPC1RAB9ASMN1; SMN2
SCHEMBL10482856 0.84 STAT3 (0.58) STAT3STAT1NPC1RAB9AALDH1A1
SCHEMBL2849607 0.84 STAT3 (0.58) STAT3STAT1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115254026-B Bismuth-based adsorption chlorine removal material and preparation method and application thereof 邯郸市赵都精细化工有限公司 2023-12-22 — — CN claimed
CN-115254026-A Bismuth-based adsorption dechlorination material and preparation method and application thereof 邯郸市赵都精细化工有限公司 2022-11-01 — — CN claimed
CN-103998974-A Optical device ESSILOR INT 2014-08-20 — — CN claimed
WO-2013084177-A1 OPHTHALMIC FILTER Essilor International (Compagnie Générale d'Optique) (FR) 2013-06-13 — — WO claimed
CN-102417510-A Conjugated Schiff base Zn (zinc) porphyrin as well as preparation and application thereof UNIV NORTHWEST NORMAL 2012-04-18 — — CN claimed
JP-56127385-A — — None — — JP disclosed
EP-3371645-B1 OPTICAL ARTICLE PROTECTING FROM BLUE LIGHT ESSILOR INT (FR) 2025-10-29 — — EP disclosed
EP-3807713-B1 COLOR-BALANCED LENSES EXHIBITING REDUCED BLUE LIGHT TRANSMITTANCE ESSILOR INT (FR) 2025-08-06 — — EP disclosed
CN-113039191-B Nucleotide analogues 奇异基因组学系统公司 2024-07-16 — — CN disclosed
CN-118265762-A Electrochromic gel and device comprising same PPG工业俄亥俄公司 2024-06-28 — — CN disclosed
US-12019316-B2 Color-balanced lenses exhibiting reduced blue light transmittance ESSILOR INTERNATIONAL (FR) 2024-06-25 — — US disclosed
EP-3296799-B1 OPTICAL ARTICLE WITH BLUE CUT, HIGH UV CUT AND HIGH CLARITY ESSILOR INT (FR) 2024-05-22 — — EP disclosed
CN-1404177-A Combination electrode used for oxygen reduction MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2003-03-19 — — CN disclosed
US-6238931-B1 PARTICLES WITH ENERGY DONORS AND ACCEPTORS AS WELL AS PROTEINS, POLYPEPTIDES, NUCLEIC ACIDS, OR LIGAND ANALOGUES BOUND TO SURFACE; WITH REDUCED QUENCHING AND IMPROVED FLUORESCENCE INTENSITIES; IMMUNOASSAYS BIOSITE DIAGNOSTICS, INC. 2001-05-29 — — US disclosed
EP-0235016-B1 Oxygen sensor TERUMO CORP (JP) 1994-08-03 — — EP disclosed
WO-1994011371-A1 TETRAPHENYLPORPHYRIN COMPOUNDS AND METHOD THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1994-05-26 — — WO disclosed
US-4957615-A POLYMER MEMBRANE WHICH CONTAINS PORPHYRIN TERUMO KABUSHIKI KAISHA (JP) 1990-09-18 — — US disclosed
US-4861454-A PORPHYRINS TERUMO KABUSHIKI KAISHA (JP) 1989-08-29 — — US disclosed
EP-0235016-A2 Oxygen sensor TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-09-02 — — EP disclosed
JP-S56127385-A CROWN-TYPE IRON TETRAPHENYLPORPHYRINE AND GAS ADSORBENT TSUCHIDA HIDETOSHI 1981-10-06 — — JP disclosed
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