SCHEMBL2849607

SCHEMBL2849607

Oc1ccccc1-c1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.58
▸ STAT1 P42224 1/20 0.58
▸ MGAM O43451 2/20 0.36
▸ KDM4E B2RXH2 3/20 0.35
▸ HPGD P15428 2/20 0.35
▸ RIPK1 Q13546 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ PDE5A O76074 1/20 0.35
▸ F2 P00734 2/20 0.35
▸ F10 P00742 2/20 0.35
▸ PLG P00747 2/20 0.35
▸ PLAU P00749 2/20 0.35
▸ PLAT P00750 2/20 0.35
▸ HPN P05981 2/20 0.35
▸ PRSS1 P07477 2/20 0.35
▸ PRSS2 P07478 2/20 0.35
▸ PRSS3 P35030 2/20 0.35
▸ ST14 Q9Y5Y6 1/20 0.35
▸ GAA P10253 2/20 0.35
▸ F7 P08709 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013624 0.86 STAT3 (0.57) STAT3STAT1F2F10PLG
SCHEMBL6727079 0.86 STAT3 (0.50) STAT3STAT1
SCHEMBL4269117 0.85 STAT3 (0.55) STAT3STAT1
SCHEMBL10482856 0.84 STAT3 (0.58) STAT3STAT1MGAMGAASI
SCHEMBL9764318 0.84 STAT3 (0.58) STAT3STAT1MGAMKDM4EGAA
SCHEMBL6892151 0.84 STAT3 (0.58) STAT3STAT1KDM4EHPGDHSD17B10
SCHEMBL27579991 0.84 STAT3 (0.58) STAT3STAT1MGAMHPGDGAA
SCHEMBL7269032 0.84 STAT3 (0.58) STAT3STAT1F2PLGPRSS1
SCHEMBL7268040 0.84 STAT3 (0.54) STAT3STAT1
SCHEMBL4268682 0.84 STAT3 (0.54) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114497724-B Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2023-05-23 — — CN claimed
CN-114497724-A Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2022-05-13 — — CN claimed
CN-111261884-B Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2021-02-12 — — CN claimed
CN-111261884-A Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2020-06-09 — — CN claimed
EP-0959879-B1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF OSTEOARTHRITIS GEN HOSPITAL CORP (US) 2004-05-06 — — EP claimed
EP-0337601-B1 PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT SCOTIA HOLDINGS PLC (GB) 1993-05-05 — — EP claimed
US-20250143897-A1 STENT-CONTAINING MEDICAL DEVICES AND METHODS OF USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-05-08 — — US disclosed
CN-119552125-A Compounds and compositions for ocular treatment 艾弗德罗股份有限公司 2025-03-04 — — CN disclosed
CN-113811527-B Bis (biaziridine) derivatives as photocrosslinkers for the treatment of keratolytic disorders 艾弗德罗股份有限公司 2024-12-31 — — CN disclosed
CN-114072149-B Compounds and compositions for ocular treatment 艾弗德罗股份有限公司 2024-11-12 — — CN disclosed
CN-117580614-A Compositions and methods for increasing sensitivity of cancer cells to alternating electric fields 诺沃库勒有限责任公司 2024-02-20 — — CN disclosed
CN-116615268-A Methods and compositions for using alternating electric fields in gene therapy 诺沃库勒有限责任公司 2023-08-18 — — CN disclosed
CN-116392590-A Preparation method and application of photosensitizer-entrapped composite nanoparticle 珠海中科先进技术研究院有限公司 2023-07-07 — — CN disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 — — WO disclosed
EP-0235016-B1 Oxygen sensor TERUMO CORP (JP) 1994-08-03 — — EP disclosed
US-5162519-A Porphyrins and cancer treatment EFAMOL HOLDINGS PLC (GB) 1992-11-10 — — US disclosed
US-4992257-A Dihydroporphyrins and method of treating tumors EFAMOL HOLDINGS PLC (GB) 1991-02-12 — — US disclosed
US-4957615-A POLYMER MEMBRANE WHICH CONTAINS PORPHYRIN TERUMO KABUSHIKI KAISHA (JP) 1990-09-18 — — US disclosed
US-4861454-A PORPHYRINS TERUMO KABUSHIKI KAISHA (JP) 1989-08-29 — — US disclosed
EP-0235016-A2 Oxygen sensor TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-09-02 — — EP disclosed
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