Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899526 | 1.00 | ADORA1 (0.58) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL26298122 | 0.93 | ADORA1 (0.57) | ADORA1ADORA2AADORA3SLC29A1ADORA2B | |
| SCHEMBL6898364 | 0.91 | ADORA1 (0.62) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL2221692 | 0.91 | ADORA2A (0.59) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL2221683 | 0.91 | ADORA2A (0.59) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL6899430 | 0.91 | ADORA1 (0.56) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL6899424 | 0.91 | ADORA1 (0.56) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL19840252 | 0.90 | LMNA (0.52) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL19407591 | 0.90 | ADORA1 (0.56) | ADORA1ADORA2AADORA3SLC29A1TP53 | |
| SCHEMBL7064871 | 0.90 | ADORA1 (0.56) | ADORA1ADORA2AADORA3SLC29A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604409-B1 | OLIGONUCLEOTIDE ANALOGS FOR DETECTING AND MODULATING RNA ACTIVITY AND GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1418179-A2 | Compositions and methods for detecting and modulating rna activity and gene expression | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-12 | — | — | EP | disclosed |