SCHEMBL6892391

SCHEMBL6892391

CCOC(=O)c1ccc(-c2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA7 P43166 2/20 0.54
CA9 Q16790 2/20 0.54
CA14 Q9ULX7 2/20 0.54
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
CYP1A2 P05177 3/20 0.53
CYP3A4 P08684 2/20 0.53
LMNA P02545 1/20 0.53
MAOA P21397 1/20 0.53
STS P08842 1/20 0.53
HPGD P15428 2/20 0.51
HTT P42858 1/20 0.51
KCNH2 Q12809 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11506065 0.95 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL1965326 0.84 CA1 (0.73) CA12CA1CA2CA7CA9
SCHEMBL16351874 0.84 CA1 (0.73) CA12CA1CA2CA7CA9
SCHEMBL10076560 0.82 ALDH1A1 (0.62) ESR1CYP1A2CYP3A4LMNASTS
SCHEMBL2997359 0.81 MAPT (0.59) CA12CA1CA2CA7CA9
SCHEMBL2721728 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL13266961 0.81 CA1 (0.58) CA12CA1CA2CA7CA9
SCHEMBL14985549 0.81 ESR1 (0.66) ESR1CYP1A2CYP3A4LMNASTS
SCHEMBL11486248 0.80 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL1638836 0.80 CA12 (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004003561-A9 PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME UNIV NORTHWESTERN (US) 2004-08-12 WO disclosed
WO-2004003561-A1 PEPTIDE ROD AMPHIPHILES AND SELF-ASSEMBLY OF SAME NORTHWESTERN UNIVERSITY (US) 2004-01-08 WO disclosed