Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382371 | 1.00 | SCD (0.59) | SCDEPHX2GPR119 | |
| SCHEMBL70228 | 0.88 | SCD (0.57) | SCD | |
| SCHEMBL29384512 | 0.88 | SCD (0.57) | SCD | |
| SCHEMBL29384233 | 0.86 | SCD (0.45) | SCDGPR119 | |
| SCHEMBL71353 | 0.86 | SCD (0.45) | SCDGPR119 | |
| SCHEMBL70209 | 0.86 | SCD (0.43) | SCD | |
| SCHEMBL29384724 | 0.86 | SCD (0.43) | SCD | |
| SCHEMBL70855 | 0.83 | SCD (0.52) | SCD | |
| SCHEMBL29382362 | 0.83 | SCD (0.52) | SCD | |
| SCHEMBL70415 | 0.83 | SCD (0.41) | SCDGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | claimed |
| EP-2268143-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | Forest Laboratories Holdings Limited (BM) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | disclosed |