SCHEMBL70228

SCHEMBL70228

O=C(NCC(=O)N1CCC(Oc2ccccc2Cl)CC1)c1cn(-c2cccnc2)nn1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 17/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384512 1.00 SCD (0.57) SCD
SCHEMBL70855 0.95 SCD (0.52) SCD
SCHEMBL29382362 0.95 SCD (0.52) SCD
SCHEMBL29385002 0.92 SCD (0.47) SCD
SCHEMBL70138 0.92 SCD (0.47) SCD
SCHEMBL69949 0.92 SCD (0.56) SCD
SCHEMBL29384494 0.92 SCD (0.56) SCD
SCHEMBL29382371 0.88 SCD (0.59) SCD
SCHEMBL68925 0.88 SCD (0.59) SCD
SCHEMBL70154 0.88 SCD (0.49) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268143-A2 NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE Forest Laboratories Holdings Limited (BM) 2011-01-05 EP claimed
US-8129376-B2 Piperidine derivatives as inhibitors of stearoyl-CoA desaturase AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2012-03-06 US disclosed
US-8129376-B2 Piperidine derivatives as inhibitors of stearoyl-CoA desaturase AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2012-03-06 US disclosed
EP-2268143-A2 NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE Forest Laboratories Holdings Limited (BM) 2011-01-05 EP disclosed