Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | NMBR | P28336 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | APAF1 | O14727 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | BRS3 | P32247 | 6/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | TACR3 | P29371 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838780 | 0.89 | POLB (0.73) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL7671885 | 0.88 | CYP3A4 (0.69) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL6894596 | 0.86 | KMT2A (0.65) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL8893203 | 0.86 | KMT2A (0.65) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL8706463 | 0.86 | KMT2A (0.65) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL7678071 | 0.85 | KDM4E (0.67) | KMT2AKDM4EMAPTMEN1TSHR | |
| Hydrochloric Acid SCHEMBL9833815 | 0.85 | HDAC8 (0.66) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL8998923 | 0.85 | KMT2A (0.64) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL8999025 | 0.85 | KMT2A (0.64) | KMT2AKDM4EMAPTMEN1TSHR | |
| SCHEMBL17017538 | 0.84 | POLB (0.69) | KMT2AKDM4EMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405537-B1 | N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives | WARNER LAMBERT CO (US) | 2004-09-08 | — | — | EP | claimed |