⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13211627 | 0.80 | — | — | |
| SCHEMBL31736424 | 0.69 | PDPK1 (0.31) | — | |
| SCHEMBL17175006 | 0.65 | — | — | |
| SCHEMBL22609431 | 0.64 | YTHDC1 (0.39) | — | |
| SCHEMBL3723182 | 0.63 | — | — | |
| SCHEMBL24121978 | 0.62 | PDPK1 (0.34) | — | |
| SCHEMBL17175024 | 0.61 | PARP14 (0.31) | — | |
| SCHEMBL26414276 | 0.60 | PDPK1 (0.30) | — | |
| SCHEMBL1585949 | 0.60 | — | — | |
| SCHEMBL10392936 | 0.60 | MB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1460074-A1 | Substituted amino alkyl compounds | CELL THERAPEUTICS, INC. (US) | 2004-09-22 | — | — | EP | claimed |
| EP-0719267-B1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS INC (US) | 2002-07-31 | — | — | EP | claimed |
| US-5985926-A | VIRICIDES OF AMINE COMPOUNDS AND HYDROCARBONS | CELL THERAPEUTICS, INC. (US) | 1999-11-16 | — | — | US | claimed |
| US-5929081-A | ADMINISTERING COMPOUND THAT INHIBITS SIGNAL TRANSDUCTION THROUGH CELLULAR ACCUMULATION OF NON-ARACHIDONYL PHOSPHATIDIC ACID | CELL THERAPEUTICS INC. (US) | 1999-07-27 | — | — | US | claimed |
| US-5859018-A | ANTIARTHRITIC AGENTS; ANTITUMOR AGENTS; CARDIOVASCULAR DISORDERS | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | claimed |
| CN-1040980-C | Second messenger cell signaling inhibitors | CELL THERAPEUTICS INC (US) | 1998-12-02 | — | — | CN | claimed |
| US-5837703-A | AUTOIMMUNE DISEASES, ARTHRITIS, CANCER, LEUKEMIA, MULTIPLE SCLEROSIS; ANTITUMOR AGENTS | CELL THERAPEUTICS, INC. (US) | 1998-11-17 | — | — | US | claimed |
| US-5795898-A | ANTITUMOR, ANTICANCER AGENTS, ANTIDIABETIC AGENTS, SKIN DISORDERS | CELL THERAPEUTICS, INC. (US) | 1998-08-18 | — | — | US | claimed |
| US-5770595-A | Oxime substituted therapeutic compounds | CELL THERAPEUTICS, INC. (US) | 1998-06-23 | — | — | US | claimed |
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0697873-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-02-28 | — | — | EP | claimed |
| EP-0719267-A4 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS INC (US) | 1996-02-16 | — | — | EP | claimed |
| EP-0623133-A4 | SUBSTITUTED AMINO ALKYL COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1995-10-11 | — | — | EP | claimed |
| WO-1994022863-A9 | SECOND MESSENGER CELL SIGNALING INHIBITORS | — | 1994-12-22 | — | — | WO | claimed |
| EP-0623133-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-11-09 | — | — | EP | claimed |
| WO-1994024133-A1 | RING-SUBSTITUTED CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | claimed |
| WO-1994022863-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | claimed |
| WO-1994015606-A1 | OLEFIN-SUBSTITUTED LONG CHAIN COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-07-21 | — | — | WO | claimed |
| WO-1994011370-A1 | SUBSTITUTED AMINO ALKYL COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | claimed |